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1

Estrogen and phenol sulfotransferase activities in human fetal lung

Alwen L. Jones, Robert Hume, Kathleen J. Bamforth, Michael W.H. Coughtrie

Journal:

Early Human Development

Année:

1992

Langue:

english

Fichier:

PDF, 916 KB

english, 1992

2

Phenol sulfotransferase 1A1 activity in human liver: kinetic properties, interindividual variation and re-evaluation of the suitability of 4-nitrophenol as a probe substrate

Catherine A. Tabrett, Michael W.H. Coughtrie

Journal:

Biochemical Pharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 173 KB

english, 2003

3

Protocol for theSmoking,NicotineandPregnancy (SNAP) trial: double-blind, placebo-randomised, controlled trial of nicotine replacement therapy in pregnancy

Tim Coleman, Jim Thornton, John Britton, Sarah Lewis, Kim Watts, Michael WH Coughtrie, Clare Mannion, Neil Marlow, Christine Godfrey

Journal:

BMC Health Services Research

Année:

2007

Langue:

english

Fichier:

PDF, 362 KB

english, 2007

4

Common food additives are potent inhibitors of human liver 17α-ethinyloestradiol and dopamine sulphotransferases

Kathleen J. Bamforth, Alwen L. Jones, Richard C. Roberts, Michael W.H. Coughtrie

Journal:

Biochemical Pharmacology

Année:

1993

Langue:

english

Fichier:

PDF, 785 KB

english, 1993

5

CoMFA Modeling of Enzyme Kinetics: Km Values for Sulfation of Diverse Phenolic Substrates by Human Catecholamine Sulfotransferase SULT1A3.

Julius Sipilae, Alan M. Hood, Michael W. H. Coughtrie, Jyrki Taskinen

Journal:

Année:

2003

Fichier:

PDF, 56 KB

2003

6

Function and regulation of UDP-glucuronosyltransferase genes in health and liver disease: Report of the seventh international workshop on glucuronidation, september 1993, Pitlochry, Scotland

Brian Burchell B.Sc. Ph.D. MCRPath., Michael W. H. Coughtrie, Peter L. M. Jansen

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 1.06 MB

english, 1994

7

Phenolsulphotransferase: localization in kidney during human embryonic and fetal development

Robert Hume, Michael W. H. Coughtrie

Journal:

Journal of Molecular Histology

Année:

1994

Langue:

english

Fichier:

PDF, 3.61 MB

english, 1994

8

Differential expression and immunohistochemical localisation of the phenol and hydroxysteroid sulphotransferase enzyme families in the developing lung

Robert Hume, Emma V. Barker, Michael W. H. Coughtrie

Journal:

Histochemistry and Cell Biology

Année:

1996

Langue:

english

Fichier:

PDF, 3.14 MB

english, 1996

9

A general assay for UDPglucuronosyltransferase activity using polar amino-cyano stationary phase HPLC and UDP[U-14C]glucuronic acid

Michael W.H. Coughtrie, Brian Burchell, John R. Bend

Journal:

Analytical Biochemistry

Année:

1986

Langue:

english

Fichier:

PDF, 661 KB

english, 1986

10

Farnesol is glucuronidated in human liver, kidney and intestine in vitro, and is a novel substrate for UGT2B7 and UGT1A1

STAINES, Adam G., SINDELAR, Pavel, COUGHTRIE, Michael W. H., BURCHELL, Brian

Journal:

Biochemical Journal

Année:

2004

Langue:

english

Fichier:

PDF, 489 KB

english, 2004

11

In VitroInhibition of Thyroid Hormone Sulfation by Polychlorobiphenylols: Isozyme Specificity and Inhibition Kinetics

A.Gerlienke Schuur, Ingeborg van Leeuwen-Bol, Willeke M.C. Jong, Åke Bergman, Michael W.H. Coughtrie, Abraham Brouwer, Theo J. Visser

Journal:

Toxicological Sciences

Année:

1998

Langue:

english

Fichier:

PDF, 118 KB

english, 1998

12

Selective induction of bilirbuin UDP-glucuronosyl-transferase by perfluorodecanoic acid

Michael Arand, Michael W.H. Coughtrie, Brian Burchell, Franz Oesch, Larry W. Robertson

Journal:

Chemico-Biological Interactions

Année:

1991

Langue:

english

Fichier:

PDF, 497 KB

english, 1991

13

Sulfation of endogenous compounds and xenobiotics — interactions and function in health and disease

Michael W.H. Coughtrie, Kathleen J. Bamforth, Sheila Sharp, Alwen L. Jones, Emma B. Borthwick, Emma V. Barker, Richard C. Roberts, Robert Hume, Ann Burchell

Journal:

Chemico-Biological Interactions

Année:

1994

Langue:

english

Fichier:

PDF, 547 KB

english, 1994

14

Sulfation of carcinogenic aromatic hydroxylamines and hydroxamic acids by rat and human sulfotransferases: substrate specificity, developmental aspects and sex differences

John H.N. Meerman, David P. Ringer, Michael W.H. Coughtrie, Kathleen J. Bamforth, Ron A.H.J. Gilissen

Journal:

Chemico-Biological Interactions

Année:

1994

Langue:

english

Fichier:

PDF, 498 KB

english, 1994

15

Effect of structurally diverse peroxisome proliferators on rat hepatic sulfotransferase

Frank Witzmann, Michael Coughtrie, Carla Fultz, John Lipscomb

Journal:

Chemico-Biological Interactions

Année:

1996

Langue:

english

Fichier:

PDF, 834 KB

english, 1996

16

Preparation and characterization of anti-peptide antibodies directed against human phenol and hydroxysteroid sulphotransferases

Sheila Sharp, Michael W.H. Coughtrie, Kathleen J. Forbes, Robert Hume

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

1995

Langue:

english

Fichier:

PDF, 793 KB

english, 1995

17

Evidence for multiple glucuronide transporters in rat liver microsomes

Miklós Csala, Adam G. Staines, Gábor Bánhegyi, József Mandl, Michael W.H. Coughtrie, Brian Burchell

Journal:

Biochemical Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 234 KB

english, 2004

18

Comparison of 2-aminophenol and 4-nitrophenol as in vitro probe substrates for the major human hepatic sulfotransferase, SULT1A1, demonstrates improved selectivity with 2-aminophenol

Zoe Riches, Jackie C. Bloomer, Michael W.H. Coughtrie

Journal:

Biochemical Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 266 KB

english, 2007

19

Regioselective sulfonation of dopamine by SULT1A3 in vitro provides a molecular explanation for the preponderance of dopamine-3-O-sulfate in human blood circulation

Katriina Itäaho, Sami Alakurtti, Jari Yli-Kauhaluoma, Jyrki Taskinen, Michael W.H. Coughtrie, Risto Kostiainen

Journal:

Biochemical Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 239 KB

english, 2007

20

Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum

Theodora G.H.A. Tucker, Alison M. Milne, Sylvie Fournel-Gigleux, Katherine S. Fenner, Michael W.H. Coughtrie

Journal:

Biochemical Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 508 KB

english, 2012

21

Molecular characterization of β1,4-galactosyltransferase 7 genetic mutations linked to the progeroid form of Ehlers–Danlos syndrome (EDS)

Catherine Bui, Ibtissam Talhaoui, Matthieu Chabel, Guillermo Mulliert, Michael W.H. Coughtrie, Mohamed Ouzzine, Sylvie Fournel-Gigleux

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 730 KB

english, 2010

22

Influence of culture system and medium enrichment on sulfotransferase and sulfatase expression in male rat hepatocyte cultures

Katrien Slaus, Michael W.H Coughtrie, Sheila Sharp, Tamara Vanhaecke, Antoine Vercruysse, Vera Rogiers

Journal:

Biochemical Pharmacology

Année:

2001

Langue:

english

Fichier:

PDF, 887 KB

english, 2001

23

Inhibition of thyroid hormone sulfation by hydroxylated metabolites of polychlorinated biphenyls

A Gerlienke Schuur, Abraham Brouwer, Åke Bergman, Michael W.H Coughtrie, Theo J Visser

Journal:

Chemico-Biological Interactions

Année:

1998

Langue:

english

Fichier:

PDF, 75 KB

english, 1998

24

Microsomal steroid sulfatase: interactions with cytosolic steroid sulfotransferases

Frederick C Kauffman, Sheila Sharp, Bernard B Allan, Ann Burchell, Michael W.H Coughtrie

Journal:

Chemico-Biological Interactions

Année:

1998

Langue:

english

Fichier:

PDF, 160 KB

english, 1998

25

Biology and function of the reversible sulfation pathway catalysed by human sulfotransferases and sulfatases

Michael W.H Coughtrie, Sheila Sharp, Kaera Maxwell, Nicola P Innes

Journal:

Chemico-Biological Interactions

Année:

1998

Langue:

english

Fichier:

PDF, 206 KB

english, 1998

26

Characterization of thyroid hormone sulfotransferases

Theo J Visser, Ellen Kaptein, Hansruedi Glatt, Ingrid Bartsch, Maria Hagen, Michael W.H Coughtrie

Journal:

Chemico-Biological Interactions

Année:

1998

Langue:

english

Fichier:

PDF, 433 KB

english, 1998

27

Sulfotransferase-mediated activation of mutagens studied using heterologous expression systems

Hansruedi Glatt, Ingrid Bartsch, Stefanie Christoph, Michael W.H Coughtrie, Charles N Falany, Maria Hagen, Robert Landsiedel, Ulrike Pabel, David H Phillips, Albrecht Seidel, Yasushi Yamazoe

Journal:

Chemico-Biological Interactions

Année:

1998

Langue:

english

Fichier:

PDF, 297 KB

english, 1998

28

Detection of a Sacl restriction fragment length polymorphism at the human phenolsulphotransferase locus

Alwen L. Jones, Richard C. Roberts, Michael W.H. Coughtrie

Journal:

Clinical Genetics

Année:

1996

Langue:

english

Fichier:

PDF, 211 KB

english, 1996

29

Inhibition of UDP-glucuronosyltransferase activity by possible transition-state analogues in rat-liver microsomes

Daan NOORT, Michael W. H. COUGHTRIE, Brian BURCHELL, Gijs A. van der MAREL, Jacques H. van BOOM, Arne van der GEN, Gerard J. MULDER

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 417 KB

english, 1990

30

Immunochemical characterisation of a dehydroepiandrosterone sulfotransferase in rats and humans

Sheila SHARP, Emma V. BARKER, Michael W. H. COUGHTRIE, Pedro R. LOWENSTEIN, Robert HUME

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 1.61 MB

english, 1993

31

Kinetic Properties of Human Dopamine Sulfotransferase (SULT1A3) Expressed in Prokaryotic and Eukaryotic Systems: Comparison with the Recombinant Enzyme Purified fromEscherichia coli

Rana Dajani, Sheila Sharp, Steven Graham, Susanne S. Bethell, Robert M. Cooke, Derek J. Jamieson, Michael W.H. Coughtrie

Journal:

Protein Expression and Purification

Année:

1999

Langue:

english

Fichier:

PDF, 195 KB

english, 1999

32

The in vivo regulation of hepatic and renal glucose-6-phosphatase by thyroxine

Michael W. Voice, Emma B. Borthwick, Michael W.H. Coughtrie, Ann Burchell

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Année:

1995

Langue:

english

Fichier:

PDF, 438 KB

english, 1995

33

Purification and properties of rat kidney UDP-glucuronosyltransferase

Michael W.H. Coughtrie, Brian Burchell, John R. Bend

Journal:

Biochemical Pharmacology

Année:

1987

Langue:

english

Fichier:

PDF, 938 KB

english, 1987

34

The enantioselective glucuronidation of morphine in rats and humans: Evidence for the involvement of more than one UDP-glucuronosyltransferase isoenzyme

Michael W.H. Coughtrie, Birgitta Ask, Anders Rane, Brian Burchell, Robert Hume

Journal:

Biochemical Pharmacology

Année:

1989

Langue:

english

Fichier:

PDF, 876 KB

english, 1989

35

Cytosolic phenol and steroid sulphotransferase activities are decreased in a sex-dependent manner in streptozotocin-induced diabetic rats

Michael W.H. Coughtrie, John Pears, Alwen L. Jones, Ann Burchell

Journal:

Biochemical Pharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 475 KB

english, 1990

36

Purification and immunochemical characterization of a rat liver sulphotransferase conjugating paracetamol

Michael W.H. Coughtrie, Sheila Sharp

Journal:

Biochemical Pharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 1.72 MB

english, 1990

37

Glucuronidation of imipramine in rabbit and human liver microsomes: assay conditions and interaction with other tertiary amine drugs

Michael W.H. Coughtrie, Sheila Sharp

Journal:

Biochemical Pharmacology

Année:

1991

Langue:

english

Fichier:

PDF, 649 KB

english, 1991

38

Steroid sulphates inhibit the rat hepatic microsomal glucose-6-phosphatase system

Hazel M. Scott, Michael W.H. Coughtrie, Ann Burchell

Journal:

Biochemical Pharmacology

Année:

1991

Langue:

english

Fichier:

PDF, 433 KB

english, 1991

39

The distribution of UDP-glucuronosyltransferases in rat liver parenchymal and nonparenchymal cells

Franz Oesch, Michael Arand, Michael W. Coughtrie, Brian Burchell, Pablo Steinberg

Journal:

Biochemical Pharmacology

Année:

1992

Langue:

english

Fichier:

PDF, 928 KB

english, 1992

40

Sulphation of N-hydroxy-4-aminobiphenyl and N-hydroxy-4-acetylaminobiphenyl by human foetal and neonatal sulphotransferase

Ron A.H.J. Gilissen, Robert Hume, John H.N. Meerman, Michael W.H. Coughtrie

Journal:

Biochemical Pharmacology

Année:

1994

Langue:

english

Fichier:

PDF, 616 KB

english, 1994

41

Effects of hypophysectomy and thyroxine on the expression of hepatic oestrogen, hydroxysteroid and phenol sulphotransferases

Emma B. Borthwick, Michael W. Voice, Ann Burchell, Michael W.H. Coughtrie

Journal:

Biochemical Pharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 732 KB

english, 1995

42

Heterogeneous expression of sulphotransferases in periportal and perivenous Hepatocytes prepared from male and female rat liver

David Tosh, Emma B. Borthwick, Sheila Sharp, Ann Burchell, Brian Burchell, Michael W.H. Coughtrie

Journal:

Biochemical Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 968 KB

english, 1996

43

The molecular basis of the inherited deficiency of androsterone UDP-glucuronyltransferase in Wistar rats

Robert B. Corser, Michael W.H. Coughtrie, Michael R. Jackson, Brian Burchell

Journal:

Année:

1987

Langue:

english

Fichier:

PDF, 512 KB

english, 1987

44

Human fetal adrenal hydroxysteroid sulphotransferase: cDNA cloning, stable expression in V79 cells and functional characterisation of the expressed enzyme

Kathleen J. Forbes, Maria Hagen, Hansruedi Glatt, Robert Hume, Michael W.H. Coughtrie

Journal:

Molecular and Cellular Endocrinology

Année:

1995

Langue:

english

Fichier:

PDF, 986 KB

english, 1995

45

cDNA cloning, functional expression, and characterization of chicken sulfotransferases belonging to the SULT1B and SULT1C families

Lesley A. Wilson, Geert E. Reyns, Veerle M. Darras, Michael W.H. Coughtrie

Journal:

Archives of Biochemistry and Biophysics

Année:

2004

Langue:

english

Fichier:

PDF, 391 KB

english, 2004

46

Sulfotransferase activities towards xenobiotics and estradiol in two marine fish species (Mullus barbatus and Lepidorhombus boscii): Characterization and inhibition by endocrine disrupters

Rebeca Martin-Skilton, Michael W.H. Coughtrie, Cinta Porte

Journal:

Aquatic Toxicology

Année:

2006

Langue:

english

Fichier:

PDF, 257 KB

english, 2006

47

Molecular Cloning, Characterisation and Ligand-bound Structure of an Azoreductase from Pseudomonas aeruginosa

Chan-Ju Wang, Christoph Hagemeier, Nawreen Rahman, Edward Lowe, Martin Noble, Michael Coughtrie, Edith Sim, Isaac Westwood

Journal:

Journal of Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 2.06 MB

english, 2007

48

Down-regulation of dehydroepiandrosterone sulfotransferase gene in human hepatocellular carcinoma

Lan-Ru Huang, Michael W.H. Coughtrie, Hey-Chi Hsu

Journal:

Molecular and Cellular Endocrinology

Année:

2005

Langue:

english

Fichier:

PDF, 251 KB

english, 2005

49

Expression profiling of human fetal cytosolic sulfotransferases involved in steroid and thyroid hormone metabolism and in detoxification

Emma L. Stanley, Robert Hume, Michael W.H. Coughtrie

Journal:

Molecular and Cellular Endocrinology

Année:

2005

Langue:

english

Fichier:

PDF, 454 KB

english, 2005

50

Activation of propane 2-nitronate to a genotoxicant in V79-derived cell lines engineered for the expression of rat hepatic sulfotransferases

Ulrich Andrae, Patricia Kreis, Michael W.H. Coughtrie, Ulrike Pabel, Walter Meinl, Ingrid Bartsch, Hansruedi Glatt

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

1999

Langue:

english

Fichier:

PDF, 355 KB

english, 1999